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Since Kuramoto proposed a model of coupled oscillators, the study of synchronization has pulled the attention from different point of views: biology, chemistry, neuroscience, etc. Such a phenomenon can be observed very often in biological systems like the flashing of fireflies, the beating of heart cells and the synaptic firing of neurons in the brain. Mathematically, those patterns arise as the natural collective behavior of an ensemble of agents that interact via periodic rules. Although the discrete agent-based models are interesting by themselves, real life situations involve a large amount $N$ of agents. In those cases, the system is described by $N$ coupled ODEs, what becomes very hard to tackle both from the analytical and numerical point of views. Fortunately, we can sometimes approximate with a single PDE that governs the macroscopic/fluid description of the system. In this talk we will focus on the Kuramoto model with non-uniform and singular coupling weights obeying Hebb’s rule in neuroscience. First, we shall introduce the agent-based system of $N$ coupled oscillators and the three associated regimes with regard to singularity: subcritical, critical and supercritical. We will propose a well-posedness theory in the sense of Filippov to tackle the presence of singularities, giving rise to global solutions with new rich behaviour: finite-time phase synchronization and clustering into distinguished groups. Later, we will introduce the corresponding kinetic Vlasov equation. It consists in a macroscopic (fluid) type model governed by a continuity equation for the probability density of oscillators along the manifold $\mathbb{T}\times \mathbb{R}$, where the (compressible) velocity field is nonlocal and self-generated. Since the kernel is singular, we will propose a well posedness theory via the concept of weak measure-valued solutions in the sense of Filippov’s flows that remains valid after eventual collisions. Indeed, such solutions emerge as rigorous mean field limit when the number $N$ of agents tends to infinity. Finally, we will conclude by stating some rates of convergence for those solutions and remarking some analogies and differences with other related models in the literature like the singular Cucker—Smale model.