Séminaire de Mathématique-Biologie

Upside Down and Inside Out: The Biomechanics of Cell Sheet Folding

par Prof. Raymond E. GOLDSTEIN (University of Cambridge & IHES)

Europe/Paris
Amphithéâtre Léon Motchane (IHES)

Amphithéâtre Léon Motchane

IHES

Le Bois-Marie 35, route de Chartres 91440 Bures-sur-Yvette
Description
Deformations of cell sheets are ubiquitous in early animal development, often arising from a complex and poorly understood interplay of cell shape changes, division, and migration. In this talk I will describe an approach to understanding such problems based on perhaps the simplest example of cell sheet folding: the “inversion” process of the algal genus Volvox, during which spherical embryos literally turn themselves inside out through a process hypothesized to arise from cell shape changes alone.  Through a combination of light sheet microscopy and elasticity theory a quantitative understanding of this process is now emerging.
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