Adrien Orué - A comparative overview of win ratio and joint frailty models for recurrent event endpoints with applications in oncology and cardiology

par Adrien Orué (Université de Bordeaux, Inserm Bordeaux Population Health U1219, BIOSTAT)

jeudi 16 oct. 2025, 13:00 → 14:00 Europe/Paris

Amphi Louis (ISPED)

Speaker: Adrien Orué from Bordeaux Population Health
Title: A comparative overview of win ratio and joint frailty models for recurrent event endpoints with applications in oncology and cardiology

This seminar will be in English

Abstract: Composite endpoints that combine recurrent non-fatal events with a terminal event (e.g., rehospitalizations and death) pose design and analysis challenges: within-patient correlation or yet informative censoring by death can bias classical time-to-first event analysis approaches. In this work, we compare two methods for such endpoints: recurrent-event win ratio and joint frailty models, with attention to inference and trial design.

 

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Former e-seminars on our YouTube channel (mostly in French): https://www.youtube.com/channel/UCURp-hEQL7k23UzGfqgEurA/videos

 

Biostatistics seminar series from the Department of Public Health from the University of Bordeaux and the Bordeaux Population Health UMR 1219 research center