Séminaire de Mathématique-Biologie

An Entropic Selection Principle in Evolutionary Theory

by Prof. Lloyd DEMETRIUS (MPI for Molecular Genetics, Berlin & Harvard University, Cambridge)

Amphithéâtre Léon Motchane (IHES)

Amphithéâtre Léon Motchane


Le Bois-Marie 35, route de Chartres 91440 Bures-sur-Yvette

The statistical measure Evolutionary Entropy characterizes Darwinian Fitness and predicts the outcome of competition for limited resources between related entities at various levels of organization: metabolic, cellular, organismic and social. I will discuss the mathematical basis of the selection principle and describe its application to the evolution of aging and the origin of age-related diseases.