Caterina Gregorio — Modeling Aging Trajectories Through Multistate and Latent Models

Thursday Nov 13, 2025, 1:00 PM → 2:00 PM Europe/Paris

Amphi Louis (ISPED)

Speaker: Caterina Gregorio from the Karolinska Institute
Title: Modeling Aging Trajectories Through Multistate and Latent Models

This seminar will be in English

Abstract: In this seminar, I will share my recent research on multistate modeling approaches to better understand aging and disease progression, and introduce my current Marie Skłodowska-Curie project. Through a simulation study, we have assessed how different currently employed methods perform when applied to multistate models for panel data, where intermittent observation poses significant challenges—particularly in aging research. Building on this, we have also explored settings where states are latent, such as in the study of multimorbidity patterns, capturing how chronic conditions cluster and evolve over time.
My most recent project, LETMEAGE, shifts the focus to geroscience and aims to model aging as a complex system. Through a joint latent modeling framework, I seek to integrate biological, phenotypic, and functional dimensions of aging to develop novel metrics that support personalized predictions and inform preventive strategies for healthy aging.

 

Calendar subscription link for the complete seminar series:
https://indico.math.cnrs.fr/category/711/events.ics

Program of the Biostatistics seminars:
https://indico.math.cnrs.fr/category/711/

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Former e-seminars on our YouTube channel (mostly in French): https://www.youtube.com/channel/UCURp-hEQL7k23UzGfqgEurA/videos

 

Biostatistics seminar series from the Department of Public Health from the University of Bordeaux and the Bordeaux Population Health UMR 1219 research center