Data science methods, in particular Artificial Intelligence (AI) and Machine Learning (ML), have shown their capabilities in solving complex problems in many fields includingmedicine. In this talk, focusing on some ongoing projects at Biomedical and Clinical Informatics Lab (BCIL), some of these techniques, designed as health decision support systems, will be briefly discussed. In particular, the speaker presents some algorithmicsolutions that can potentially create effective and practically useful methods to analyze complex medical and pharmaceutical data.