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SUMMARY:Switching Between Two Modes of Cell Life: Growth & Conservation
DTSTART:20260416T093000Z
DTEND:20260416T110000Z
DTSTAMP:20260426T014800Z
UID:indico-event-16439@indico.math.cnrs.fr
CONTACT:cecile@ihes.fr
DESCRIPTION:Speakers: Nava Segev (University of Illinois\, Chicago & IHES)
 \n\nDepending on nutrient availability\, cells switch between two differen
 t modes: growth\, which requires secretion\, and conservation\, which requ
 ires autophagy\, a cellular recycling pathway. The mechanisms underlying t
 he switch between these two modes are not clear. We propose that the evolu
 tionary-conserved Ypt1/Rab1 GTPase\, which is essential for the beginning 
 of secretion and macro-autophagy pathways from yeast to human\, coordinate
  this switch by functioning in two different “GTPase Modules” that inc
 lude “pathway-specific” upstream activators and downstream effectors.
       \n\nhttps://indico.math.cnrs.fr/event/16439/
LOCATION:Bâtiment Alix et Marwan Lahoud (IHES)
URL:https://indico.math.cnrs.fr/event/16439/
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