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SUMMARY:Angélique Stéphanou (TIMC Grenoble)
DTSTART:20260615T090000Z
DTEND:20260615T110000Z
DTSTAMP:20260610T181800Z
UID:indico-event-16178@indico.math.cnrs.fr
DESCRIPTION:The seminar will take place on Zoom at the following link: htt
 ps://univ-cotedazur.zoom.us/j/5698369814Short URLNone\nTitle: \nMechanics-
 driven long range communication between cells\nAbstract : \nMechanics-driv
 en communication between cells is essential for processes like angiogenesi
 s\, yet its integration into computational models remains limited. We deve
 loped a hybrid continuous-discrete model to study how mechanical cues infl
 uence cell migration on elastic fiber matrices. Refinement of the model re
 quires to represent cells as mechanosensitive networks\, where adhesions a
 nd filopodia interact dynamically with the substrate. Simulations demonstr
 ate that cells adapt their migration patterns based on substrate propertie
 s\, reproducing experimentally observed behaviors such as persistent rando
 m walks and migration bias on anisotropic substrates. This work provides a
  mechanistic framework to explore how mechanical signals mediate long-rang
 e communication between cells\, offering insights into tissue morphogenesi
 s and collective cell dynamics. \n\nhttps://indico.math.cnrs.fr/event/161
 78/
URL:https://indico.math.cnrs.fr/event/16178/
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