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SUMMARY:Developing Microbiome-directed Therapeutics for  Treating Childhoo
 d Undernutrition
DTSTART:20250618T123000Z
DTEND:20250618T133000Z
DTSTAMP:20260423T021500Z
UID:indico-event-14495@indico.math.cnrs.fr
CONTACT:cecile@ihes.fr
DESCRIPTION:Speakers: Jeffrey I. Gordon (The Edison Family Center for Geno
 me Sciences and Systems Biology\, and Center for Gut Microbiome and Nutrit
 ion Research\, Washington University School of Medicine\, St. Louis)\n\nHu
 man postnatal development is typically viewed from the perspective of our 
 ‘human’ organs.  As we come to appreciate how our microbial communiti
 es are assembled following birth\, there is an opportunity to determine ho
 w this microbial facet of our developmental biology is related to healthy 
 growth as well as to the risk for and manifestations of disorders that pro
 duce abnormal growth. We are testing the hypothesis that perturbations in 
 the normal development of the gut microbiome are causally related to child
 hood undernutrition\, a devastating global health problem whose long-term 
 sequelae\, including stunting\, neurodevelopmental abnormalities\, plus me
 tabolic and immune dysfunction\, remain largely refractory to current ther
 apeutic interventions. The journey to preclinical proof-of-concept\, and t
 he path forward to clinical proof-of-concept emphasize the opportunities a
 s well as the experimental\, analytic and other challenges encountered whe
 n developing microbiota-directed therapeutics.\n \n \n\nhttps://indico.m
 ath.cnrs.fr/event/14495/
LOCATION:Bâtiment Alix et Marwan Lahoud (IHES)
URL:https://indico.math.cnrs.fr/event/14495/
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